0.1.0 - ci-build
0.1.0 - ci-build
HL7CGModels - Local Development build (v0.1.0). See the Directory of published versions
| Active as of 2022-03-10 |
XML representation of the MolecularVariant logical model.
<StructureDefinition xmlns="http://hl7.org/fhir">
<id value="MolecularVariant"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;"><tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top"><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/formats.html#table" title="The logical name of the element">Name</a></th><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/formats.html#table" title="Information about the use of the element">Flags</a></th><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/formats.html#table" title="Minimum and Maximum # of times the the element can appear in the instance">Card.</a></th><th style="width: 100px" class="hierarchy"><a href="http://hl7.org/fhir/R4/formats.html#table" title="Reference to the type of the element">Type</a></th><th style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/formats.html#table" title="Additional information about the element">Description & Constraints</a><span style="float: right"><a href="http://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="http://hl7.org/fhir/R4/help16.png" alt="doco" style="background-color: inherit"/></a></span></th></tr><tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_element.gif" alt="." style="background-color: white; background-color: inherit" title="Element" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant" title="MolecularVariant resource">MolecularVariant</a><a name="MolecularVariant"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><span style="opacity: 0.5">0</span><span style="opacity: 0.5">..</span><span style="opacity: 0.5">*</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/domainresource.html">DomainResource</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Molecular Variant</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.molecularType" title="The type of molecule (e.g., DNA, RNA, protein)">molecularType</a><a name="MolecularVariant.molecularType"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Molecule type</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation" title="A representation for the Variant that is used as its primary definition.">primaryRepresentation</a><a name="MolecularVariant.primaryRepresentation"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Primary Representation</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.identifier" title="Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.">identifier</a><a name="MolecularVariant.primaryRepresentation.identifier"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Identifer</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck111.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.text" title="Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.">text</a><a name="MolecularVariant.primaryRepresentation.text"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Text</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.text.value" title="Value for the textual representation">value</a><a name="MolecularVariant.primaryRepresentation.text.value"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#string">string</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Value</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.text.system" title="System that defines the nomenclature (including version, if applicable)">system</a><a name="MolecularVariant.primaryRepresentation.text.system"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">System</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence" title="Sequence based representation of a variant">sequence</a><a name="MolecularVariant.primaryRepresentation.sequence"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Sequence</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.system" title="The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)">system</a><a name="MolecularVariant.primaryRepresentation.sequence.system"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">System</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_choice.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Choice of Types" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]" title="Sequence used as a reference for defining the state expressed by the Variant">referenceSequence[x]</a><a name="MolecularVariant.primaryRepresentation.sequence.referenceSequence_x_"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Reference Sequence</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <span title="Datatype to support FHIR Genomics. This datatype supports representations like GRCH38.p13 Chromosome 1">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-GenomeSequenceDesignation.html">http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <span title="Datatype to support FHIR Genomics. This datatype supports identifier/accession-style representations like GCA_000001405.28">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-IdentifierSequenceDesignation.html">http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_resource.png" alt="." style="background-color: white; background-color: inherit" title="Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.interval" title="Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).">interval</a><a name="MolecularVariant.primaryRepresentation.sequence.interval"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-MolecularPreciseInterval.html">http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Interval</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.referenceAllele" title="The allele found in the Reference Sequence at the location specified by Interval.">referenceAllele</a><a name="MolecularVariant.primaryRepresentation.sequence.referenceAllele"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-MolecularSequence.html">Molecular Sequence</a>)</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Reference Allele</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="." style="background-color: white; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.alternateAllele" title="The state of the sequence at the location specified by Interval, which defines this Variant.">alternateAllele</a><a name="MolecularVariant.primaryRepresentation.sequence.alternateAllele"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-MolecularSequence.html">Molecular Sequence</a>)</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Alternate Allele</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation" title="Alternative representations of the variant that might be considered to be equivalent but which might contain ambiguity or imprecision. Lossless transformations between the Primary and Secondary Representation(s) are not guaranteed.">secondaryRepresentation</a><a name="MolecularVariant.secondaryRepresentation"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Secondary Representation(s)<br/></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.identifier" title="Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.">identifier</a><a name="MolecularVariant.secondaryRepresentation.identifier"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Identifer</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck111.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.text" title="Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.">text</a><a name="MolecularVariant.secondaryRepresentation.text"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Text</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.text.value" title="Value for the textual representation">value</a><a name="MolecularVariant.secondaryRepresentation.text.value"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#string">string</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Value</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.text.system" title="System that defines the nomenclature (including version, if applicable)">system</a><a name="MolecularVariant.secondaryRepresentation.text.system"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">System</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence" title="Sequence based representation of a variant">sequence</a><a name="MolecularVariant.secondaryRepresentation.sequence"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Sequence</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.system" title="The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)">system</a><a name="MolecularVariant.secondaryRepresentation.sequence.system"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">System</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1011.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_choice.gif" alt="." style="background-color: white; background-color: inherit" title="Choice of Types" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]" title="Sequence used as a reference for defining the state expressed by the Variant">referenceSequence[x]</a><a name="MolecularVariant.secondaryRepresentation.sequence.referenceSequence_x_"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Reference Sequence</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10110.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <span title="Datatype to support FHIR Genomics. This datatype supports representations like GRCH38.p13 Chromosome 1">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</span></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-GenomeSequenceDesignation.html">http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10100.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <span title="Datatype to support FHIR Genomics. This datatype supports identifier/accession-style representations like GCA_000001405.28">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</span></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-IdentifierSequenceDesignation.html">http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_resource.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.interval" title="Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).">interval</a><a name="MolecularVariant.secondaryRepresentation.sequence.interval"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="StructureDefinition-MolecularPreciseInterval.html">http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Interval</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="." style="background-color: white; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.referenceAllele" title="The allele found in the Reference Sequence at the location specified by Interval.">referenceAllele</a><a name="MolecularVariant.secondaryRepresentation.sequence.referenceAllele"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-MolecularSequence.html">Molecular Sequence</a>)</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Reference Allele</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vline.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.alternateAllele" title="The state of the sequence at the location specified by Interval, which defines this Variant.">alternateAllele</a><a name="MolecularVariant.secondaryRepresentation.sequence.alternateAllele"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-MolecularSequence.html">Molecular Sequence</a>)</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Alternate Allele</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: white; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships" title="Defines a relationship between the source Variant and a target Variant.">relationships</a><a name="MolecularVariant.relationships"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..*</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#BackboneElement">BackboneElement</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Relationship to another Variant<br/></td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_datatype.gif" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships.type" title="Type of relationship (e.g., a genomic variant might have a relationship of 'predicted translation to' a variant expressed at the protein level)">type</a><a name="MolecularVariant.relationships.type"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#CodeableConcept">CodeableConcept</a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Type</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white"><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck010.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_primitive.png" alt="." style="background-color: white; background-color: inherit" title="Primitive Data Type" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships.description" title="Text description of the relationship">description</a><a name="MolecularVariant.relationships.description"> </a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">0..1</td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/datatypes.html#string">string</a></td><td style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Description</td></tr>
<tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7"><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck000.png)" class="hierarchy"><img src="tbl_spacer.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_blank.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="tbl_vjoin_end.png" alt="." style="background-color: inherit" class="hierarchy"/><img src="icon_reference.png" alt="." style="background-color: #F7F7F7; background-color: inherit" title="Reference to another Resource" class="hierarchy"/> <a href="StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships.relatedVariant" title="Target variant of the relationship">relatedVariant</a><a name="MolecularVariant.relationships.relatedVariant"> </a></td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"/><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">1..1</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy"><a href="http://hl7.org/fhir/R4/references.html">Reference</a>(<a href="StructureDefinition-MolecularVariant.html">Molecular Variant</a>)</td><td style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px" class="hierarchy">Related Variant</td></tr>
<tr><td colspan="5" class="hierarchy"><br/><a href="http://hl7.org/fhir/R4/formats.html#table" title="Legend for this format"><img src="http://hl7.org/fhir/R4/help16.png" alt="doco" style="background-color: inherit"/> Documentation for this format</a></td></tr></table></div>
</text>
<url
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant"/>
<version value="0.1.0"/>
<name value="MolecularVariant"/>
<title value="Molecular Variant"/>
<status value="active"/>
<date value="2022-03-10T10:18:50-06:00"/>
<publisher value="Clinical Genomics"/>
<contact>
<name value="Clinical Genomics"/>
<telecom>
<system value="url"/>
<value value="http://example.org/example-publisher"/>
</telecom>
</contact>
<description value="MolecularVariant resource"/>
<jurisdiction>
<coding>
<system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
<code value="001"/>
<display value="World"/>
</coding>
</jurisdiction>
<fhirVersion value="4.0.1"/>
<mapping>
<identity value="rim"/>
<uri value="http://hl7.org/v3"/>
<name value="RIM Mapping"/>
</mapping>
<kind value="logical"/>
<abstract value="false"/>
<type
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant"/>
<baseDefinition value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
<derivation value="specialization"/>
<snapshot>
<element id="MolecularVariant">
<path value="MolecularVariant"/>
<short value="Molecular Variant"/>
<definition value="MolecularVariant resource"/>
<min value="0"/>
<max value="*"/>
<base>
<path value="DomainResource"/>
<min value="0"/>
<max value="*"/>
</base>
<constraint>
<key value="dom-2"/>
<severity value="error"/>
<human
value="If the resource is contained in another resource, it SHALL NOT contain nested Resources"/>
<expression value="contained.contained.empty()"/>
<xpath value="not(parent::f:contained and f:contained)"/>
<source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
</constraint>
<constraint>
<key value="dom-3"/>
<severity value="error"/>
<human
value="If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource"/>
<expression
value="contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()"/>
<xpath
value="not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))"/>
<source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
</constraint>
<constraint>
<key value="dom-4"/>
<severity value="error"/>
<human
value="If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated"/>
<expression
value="contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()"/>
<xpath
value="not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))"/>
<source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
</constraint>
<constraint>
<key value="dom-5"/>
<severity value="error"/>
<human
value="If a resource is contained in another resource, it SHALL NOT have a security label"/>
<expression value="contained.meta.security.empty()"/>
<xpath value="not(exists(f:contained/*/f:meta/f:security))"/>
<source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
</constraint>
<constraint>
<extension
url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice">
<valueBoolean value="true"/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation">
<valueMarkdown
value="When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."/>
</extension>
<key value="dom-6"/>
<severity value="warning"/>
<human value="A resource should have narrative for robust management"/>
<expression value="text.`div`.exists()"/>
<xpath value="exists(f:text/h:div)"/>
<source value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
</constraint>
<isModifier value="false"/>
<isSummary value="false"/>
<mapping>
<identity value="rim"/>
<map value="Entity. Role, or Act"/>
</mapping>
</element>
<element id="MolecularVariant.id">
<path value="MolecularVariant.id"/>
<short value="Logical id of this artifact"/>
<definition
value="The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes."/>
<comment
value="The only time that a resource does not have an id is when it is being submitted to the server using a create operation."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="Resource.id"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
<valueUrl value="string"/>
</extension>
<code value="http://hl7.org/fhirpath/System.String"/>
</type>
<isModifier value="false"/>
<isSummary value="true"/>
</element>
<element id="MolecularVariant.meta">
<path value="MolecularVariant.meta"/>
<short value="Metadata about the resource"/>
<definition
value="The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="Resource.meta"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="Meta"/>
</type>
<constraint>
<key value="ele-1"/>
<severity value="error"/>
<human value="All FHIR elements must have a @value or children"/>
<expression value="hasValue() or (children().count() > id.count())"/>
<xpath value="@value|f:*|h:div"/>
<source value="http://hl7.org/fhir/StructureDefinition/Element"/>
</constraint>
<isModifier value="false"/>
<isSummary value="true"/>
</element>
<element id="MolecularVariant.implicitRules">
<path value="MolecularVariant.implicitRules"/>
<short value="A set of rules under which this content was created"/>
<definition
value="A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc."/>
<comment
value="Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="Resource.implicitRules"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="uri"/>
</type>
<constraint>
<key value="ele-1"/>
<severity value="error"/>
<human value="All FHIR elements must have a @value or children"/>
<expression value="hasValue() or (children().count() > id.count())"/>
<xpath value="@value|f:*|h:div"/>
<source value="http://hl7.org/fhir/StructureDefinition/Element"/>
</constraint>
<isModifier value="true"/>
<isModifierReason
value="This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation"/>
<isSummary value="true"/>
</element>
<element id="MolecularVariant.language">
<path value="MolecularVariant.language"/>
<short value="Language of the resource content"/>
<definition value="The base language in which the resource is written."/>
<comment
value="Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute)."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="Resource.language"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="code"/>
</type>
<constraint>
<key value="ele-1"/>
<severity value="error"/>
<human value="All FHIR elements must have a @value or children"/>
<expression value="hasValue() or (children().count() > id.count())"/>
<xpath value="@value|f:*|h:div"/>
<source value="http://hl7.org/fhir/StructureDefinition/Element"/>
</constraint>
<isModifier value="false"/>
<isSummary value="false"/>
<binding>
<extension
url="http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet">
<valueCanonical value="http://hl7.org/fhir/ValueSet/all-languages"/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
<valueString value="Language"/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding">
<valueBoolean value="true"/>
</extension>
<strength value="preferred"/>
<description value="A human language."/>
<valueSet value="http://hl7.org/fhir/ValueSet/languages"/>
</binding>
</element>
<element id="MolecularVariant.text">
<path value="MolecularVariant.text"/>
<short value="Text summary of the resource, for human interpretation"/>
<definition
value="A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety."/>
<comment
value="Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later."/>
<alias value="narrative"/>
<alias value="html"/>
<alias value="xhtml"/>
<alias value="display"/>
<min value="0"/>
<max value="1"/>
<base>
<path value="DomainResource.text"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="Narrative"/>
</type>
<constraint>
<key value="ele-1"/>
<severity value="error"/>
<human value="All FHIR elements must have a @value or children"/>
<expression value="hasValue() or (children().count() > id.count())"/>
<xpath value="@value|f:*|h:div"/>
<source value="http://hl7.org/fhir/StructureDefinition/Element"/>
</constraint>
<isModifier value="false"/>
<isSummary value="false"/>
<mapping>
<identity value="rim"/>
<map value="Act.text?"/>
</mapping>
</element>
<element id="MolecularVariant.contained">
<path value="MolecularVariant.contained"/>
<short value="Contained, inline Resources"/>
<definition
value="These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope."/>
<comment
value="This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels."/>
<alias value="inline resources"/>
<alias value="anonymous resources"/>
<alias value="contained resources"/>
<min value="0"/>
<max value="*"/>
<base>
<path value="DomainResource.contained"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="Resource"/>
</type>
<isModifier value="false"/>
<isSummary value="false"/>
<mapping>
<identity value="rim"/>
<map value="N/A"/>
</mapping>
</element>
<element id="MolecularVariant.extension">
<path value="MolecularVariant.extension"/>
<slicing>
<discriminator>
<type value="value"/>
<path value="url"/>
</discriminator>
<description value="Extensions are always sliced by (at least) url"/>
<rules value="open"/>
</slicing>
<short value="Additional content defined by implementations"/>
<definition
value="May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
<comment
value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
<alias value="extensions"/>
<alias value="user content"/>
<min value="0"/>
<max value="*"/>
<base>
<path value="DomainResource.extension"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="Extension"/>
</type>
<constraint>
<key value="ele-1"/>
<severity value="error"/>
<human value="All FHIR elements must have a @value or children"/>
<expression value="hasValue() or (children().count() > id.count())"/>
<xpath value="@value|f:*|h:div"/>
<source value="http://hl7.org/fhir/StructureDefinition/Element"/>
</constraint>
<constraint>
<key value="ext-1"/>
<severity value="error"/>
<human value="Must have either extensions or value[x], not both"/>
<expression value="extension.exists() != value.exists()"/>
<xpath
value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), "value")])"/>
<source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
</constraint>
<isModifier value="false"/>
<isSummary value="false"/>
<mapping>
<identity value="rim"/>
<map value="N/A"/>
</mapping>
</element>
<element id="MolecularVariant.modifierExtension">
<path value="MolecularVariant.modifierExtension"/>
<slicing>
<discriminator>
<type value="value"/>
<path value="url"/>
</discriminator>
<description value="Extensions are always sliced by (at least) url"/>
<rules value="open"/>
</slicing>
<short value="Extensions that cannot be ignored"/>
<definition
value="May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.
Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)."/>
<comment
value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
<requirements
value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)."/>
<alias value="extensions"/>
<alias value="user content"/>
<min value="0"/>
<max value="*"/>
<base>
<path value="DomainResource.modifierExtension"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="Extension"/>
</type>
<constraint>
<key value="ele-1"/>
<severity value="error"/>
<human value="All FHIR elements must have a @value or children"/>
<expression value="hasValue() or (children().count() > id.count())"/>
<xpath value="@value|f:*|h:div"/>
<source value="http://hl7.org/fhir/StructureDefinition/Element"/>
</constraint>
<constraint>
<key value="ext-1"/>
<severity value="error"/>
<human value="Must have either extensions or value[x], not both"/>
<expression value="extension.exists() != value.exists()"/>
<xpath
value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), "value")])"/>
<source value="http://hl7.org/fhir/StructureDefinition/Extension"/>
</constraint>
<isModifier value="true"/>
<isModifierReason
value="Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them"/>
<isSummary value="false"/>
<mapping>
<identity value="rim"/>
<map value="N/A"/>
</mapping>
</element>
<element id="MolecularVariant.molecularType">
<path value="MolecularVariant.molecularType"/>
<short value="Molecule type"/>
<definition value="The type of molecule (e.g., DNA, RNA, protein)"/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.molecularType"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation">
<path value="MolecularVariant.primaryRepresentation"/>
<short value="Primary Representation"/>
<definition
value="A representation for the Variant that is used as its primary definition."/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.identifier">
<path value="MolecularVariant.primaryRepresentation.identifier"/>
<short value="Identifer"/>
<definition
value="Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.identifier"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.text">
<path value="MolecularVariant.primaryRepresentation.text"/>
<short value="Text"/>
<definition
value="Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.text"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.text.value">
<path value="MolecularVariant.primaryRepresentation.text.value"/>
<short value="Value"/>
<definition value="Value for the textual representation"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.text.value"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="string"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.text.system">
<path value="MolecularVariant.primaryRepresentation.text.system"/>
<short value="System"/>
<definition
value="System that defines the nomenclature (including version, if applicable)"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.text.system"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.sequence">
<path value="MolecularVariant.primaryRepresentation.sequence"/>
<short value="Sequence"/>
<definition value="Sequence based representation of a variant"/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.sequence"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.sequence.system">
<path value="MolecularVariant.primaryRepresentation.sequence.system"/>
<short value="System"/>
<definition
value="The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.sequence.system"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element
id="MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]">
<path
value="MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]"/>
<short value="Reference Sequence"/>
<definition
value="Sequence used as a reference for defining the state expressed by the Variant"/>
<min value="1"/>
<max value="1"/>
<base>
<path
value="MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"/>
</type>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.sequence.interval">
<path value="MolecularVariant.primaryRepresentation.sequence.interval"/>
<short value="Interval"/>
<definition
value="Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based)."/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.primaryRepresentation.sequence.interval"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"/>
</type>
</element>
<element
id="MolecularVariant.primaryRepresentation.sequence.referenceAllele">
<path
value="MolecularVariant.primaryRepresentation.sequence.referenceAllele"/>
<short value="Reference Allele"/>
<definition
value="The allele found in the Reference Sequence at the location specified by Interval."/>
<min value="0"/>
<max value="1"/>
<base>
<path
value="MolecularVariant.primaryRepresentation.sequence.referenceAllele"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element
id="MolecularVariant.primaryRepresentation.sequence.alternateAllele">
<path
value="MolecularVariant.primaryRepresentation.sequence.alternateAllele"/>
<short value="Alternate Allele"/>
<definition
value="The state of the sequence at the location specified by Interval, which defines this Variant."/>
<min value="1"/>
<max value="1"/>
<base>
<path
value="MolecularVariant.primaryRepresentation.sequence.alternateAllele"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation">
<path value="MolecularVariant.secondaryRepresentation"/>
<short value="Secondary Representation(s)"/>
<definition
value="Alternative representations of the variant that might be considered to be equivalent but which might contain ambiguity or imprecision. Lossless transformations between the Primary and Secondary Representation(s) are not guaranteed."/>
<min value="0"/>
<max value="*"/>
<base>
<path value="MolecularVariant.secondaryRepresentation"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.identifier">
<path value="MolecularVariant.secondaryRepresentation.identifier"/>
<short value="Identifer"/>
<definition
value="Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.identifier"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.text">
<path value="MolecularVariant.secondaryRepresentation.text"/>
<short value="Text"/>
<definition
value="Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles."/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.text"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.text.value">
<path value="MolecularVariant.secondaryRepresentation.text.value"/>
<short value="Value"/>
<definition value="Value for the textual representation"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.text.value"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="string"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.text.system">
<path value="MolecularVariant.secondaryRepresentation.text.system"/>
<short value="System"/>
<definition
value="System that defines the nomenclature (including version, if applicable)"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.text.system"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.sequence">
<path value="MolecularVariant.secondaryRepresentation.sequence"/>
<short value="Sequence"/>
<definition value="Sequence based representation of a variant"/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.sequence"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.sequence.system">
<path value="MolecularVariant.secondaryRepresentation.sequence.system"/>
<short value="System"/>
<definition
value="The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.sequence.system"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element
id="MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]">
<path
value="MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]"/>
<short value="Reference Sequence"/>
<definition
value="Sequence used as a reference for defining the state expressed by the Variant"/>
<min value="1"/>
<max value="1"/>
<base>
<path
value="MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"/>
</type>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.sequence.interval">
<path value="MolecularVariant.secondaryRepresentation.sequence.interval"/>
<short value="Interval"/>
<definition
value="Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based)."/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.secondaryRepresentation.sequence.interval"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"/>
</type>
</element>
<element
id="MolecularVariant.secondaryRepresentation.sequence.referenceAllele">
<path
value="MolecularVariant.secondaryRepresentation.sequence.referenceAllele"/>
<short value="Reference Allele"/>
<definition
value="The allele found in the Reference Sequence at the location specified by Interval."/>
<min value="0"/>
<max value="1"/>
<base>
<path
value="MolecularVariant.secondaryRepresentation.sequence.referenceAllele"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element
id="MolecularVariant.secondaryRepresentation.sequence.alternateAllele">
<path
value="MolecularVariant.secondaryRepresentation.sequence.alternateAllele"/>
<short value="Alternate Allele"/>
<definition
value="The state of the sequence at the location specified by Interval, which defines this Variant."/>
<min value="1"/>
<max value="1"/>
<base>
<path
value="MolecularVariant.secondaryRepresentation.sequence.alternateAllele"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element id="MolecularVariant.relationships">
<path value="MolecularVariant.relationships"/>
<short value="Relationship to another Variant"/>
<definition
value="Defines a relationship between the source Variant and a target Variant."/>
<min value="0"/>
<max value="*"/>
<base>
<path value="MolecularVariant.relationships"/>
<min value="0"/>
<max value="*"/>
</base>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.relationships.type">
<path value="MolecularVariant.relationships.type"/>
<short value="Type"/>
<definition
value="Type of relationship (e.g., a genomic variant might have a relationship of 'predicted translation to' a variant expressed at the protein level)"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.relationships.type"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.relationships.description">
<path value="MolecularVariant.relationships.description"/>
<short value="Description"/>
<definition value="Text description of the relationship"/>
<min value="0"/>
<max value="1"/>
<base>
<path value="MolecularVariant.relationships.description"/>
<min value="0"/>
<max value="1"/>
</base>
<type>
<code value="string"/>
</type>
</element>
<element id="MolecularVariant.relationships.relatedVariant">
<path value="MolecularVariant.relationships.relatedVariant"/>
<short value="Related Variant"/>
<definition value="Target variant of the relationship"/>
<min value="1"/>
<max value="1"/>
<base>
<path value="MolecularVariant.relationships.relatedVariant"/>
<min value="1"/>
<max value="1"/>
</base>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant"/>
</type>
</element>
</snapshot>
<differential>
<element id="MolecularVariant">
<path value="MolecularVariant"/>
<short value="Molecular Variant"/>
<definition value="MolecularVariant resource"/>
</element>
<element id="MolecularVariant.molecularType">
<path value="MolecularVariant.molecularType"/>
<short value="Molecule type"/>
<definition value="The type of molecule (e.g., DNA, RNA, protein)"/>
<min value="0"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation">
<path value="MolecularVariant.primaryRepresentation"/>
<short value="Primary Representation"/>
<definition
value="A representation for the Variant that is used as its primary definition."/>
<min value="1"/>
<max value="1"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.identifier">
<path value="MolecularVariant.primaryRepresentation.identifier"/>
<short value="Identifer"/>
<definition
value="Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.text">
<path value="MolecularVariant.primaryRepresentation.text"/>
<short value="Text"/>
<definition
value="Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.text.value">
<path value="MolecularVariant.primaryRepresentation.text.value"/>
<short value="Value"/>
<definition value="Value for the textual representation"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="string"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.text.system">
<path value="MolecularVariant.primaryRepresentation.text.system"/>
<short value="System"/>
<definition
value="System that defines the nomenclature (including version, if applicable)"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.sequence">
<path value="MolecularVariant.primaryRepresentation.sequence"/>
<short value="Sequence"/>
<definition value="Sequence based representation of a variant"/>
<min value="0"/>
<max value="1"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.sequence.system">
<path value="MolecularVariant.primaryRepresentation.sequence.system"/>
<short value="System"/>
<definition
value="The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element
id="MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]">
<path
value="MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]"/>
<short value="Reference Sequence"/>
<definition
value="Sequence used as a reference for defining the state expressed by the Variant"/>
<min value="1"/>
<max value="1"/>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"/>
</type>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"/>
</type>
</element>
<element id="MolecularVariant.primaryRepresentation.sequence.interval">
<path value="MolecularVariant.primaryRepresentation.sequence.interval"/>
<short value="Interval"/>
<definition
value="Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based)."/>
<min value="1"/>
<max value="1"/>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"/>
</type>
</element>
<element
id="MolecularVariant.primaryRepresentation.sequence.referenceAllele">
<path
value="MolecularVariant.primaryRepresentation.sequence.referenceAllele"/>
<short value="Reference Allele"/>
<definition
value="The allele found in the Reference Sequence at the location specified by Interval."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element
id="MolecularVariant.primaryRepresentation.sequence.alternateAllele">
<path
value="MolecularVariant.primaryRepresentation.sequence.alternateAllele"/>
<short value="Alternate Allele"/>
<definition
value="The state of the sequence at the location specified by Interval, which defines this Variant."/>
<min value="1"/>
<max value="1"/>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation">
<path value="MolecularVariant.secondaryRepresentation"/>
<short value="Secondary Representation(s)"/>
<definition
value="Alternative representations of the variant that might be considered to be equivalent but which might contain ambiguity or imprecision. Lossless transformations between the Primary and Secondary Representation(s) are not guaranteed."/>
<min value="0"/>
<max value="*"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.identifier">
<path value="MolecularVariant.secondaryRepresentation.identifier"/>
<short value="Identifer"/>
<definition
value="Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.text">
<path value="MolecularVariant.secondaryRepresentation.text"/>
<short value="Text"/>
<definition
value="Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.text.value">
<path value="MolecularVariant.secondaryRepresentation.text.value"/>
<short value="Value"/>
<definition value="Value for the textual representation"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="string"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.text.system">
<path value="MolecularVariant.secondaryRepresentation.text.system"/>
<short value="System"/>
<definition
value="System that defines the nomenclature (including version, if applicable)"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.sequence">
<path value="MolecularVariant.secondaryRepresentation.sequence"/>
<short value="Sequence"/>
<definition value="Sequence based representation of a variant"/>
<min value="0"/>
<max value="1"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.sequence.system">
<path value="MolecularVariant.secondaryRepresentation.sequence.system"/>
<short value="System"/>
<definition
value="The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element
id="MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]">
<path
value="MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]"/>
<short value="Reference Sequence"/>
<definition
value="Sequence used as a reference for defining the state expressed by the Variant"/>
<min value="1"/>
<max value="1"/>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"/>
</type>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"/>
</type>
</element>
<element id="MolecularVariant.secondaryRepresentation.sequence.interval">
<path value="MolecularVariant.secondaryRepresentation.sequence.interval"/>
<short value="Interval"/>
<definition
value="Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based)."/>
<min value="1"/>
<max value="1"/>
<type>
<code
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"/>
</type>
</element>
<element
id="MolecularVariant.secondaryRepresentation.sequence.referenceAllele">
<path
value="MolecularVariant.secondaryRepresentation.sequence.referenceAllele"/>
<short value="Reference Allele"/>
<definition
value="The allele found in the Reference Sequence at the location specified by Interval."/>
<min value="0"/>
<max value="1"/>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element
id="MolecularVariant.secondaryRepresentation.sequence.alternateAllele">
<path
value="MolecularVariant.secondaryRepresentation.sequence.alternateAllele"/>
<short value="Alternate Allele"/>
<definition
value="The state of the sequence at the location specified by Interval, which defines this Variant."/>
<min value="1"/>
<max value="1"/>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"/>
</type>
</element>
<element id="MolecularVariant.relationships">
<path value="MolecularVariant.relationships"/>
<short value="Relationship to another Variant"/>
<definition
value="Defines a relationship between the source Variant and a target Variant."/>
<min value="0"/>
<max value="*"/>
<type>
<code value="BackboneElement"/>
</type>
</element>
<element id="MolecularVariant.relationships.type">
<path value="MolecularVariant.relationships.type"/>
<short value="Type"/>
<definition
value="Type of relationship (e.g., a genomic variant might have a relationship of 'predicted translation to' a variant expressed at the protein level)"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="CodeableConcept"/>
</type>
</element>
<element id="MolecularVariant.relationships.description">
<path value="MolecularVariant.relationships.description"/>
<short value="Description"/>
<definition value="Text description of the relationship"/>
<min value="0"/>
<max value="1"/>
<type>
<code value="string"/>
</type>
</element>
<element id="MolecularVariant.relationships.relatedVariant">
<path value="MolecularVariant.relationships.relatedVariant"/>
<short value="Related Variant"/>
<definition value="Target variant of the relationship"/>
<min value="1"/>
<max value="1"/>
<type>
<code value="Reference"/>
<targetProfile
value="http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant"/>
</type>
</element>
</differential>
</StructureDefinition>