0.1.0 - ci-build
0.1.0 - ci-build
HL7CGModels - Local Development build (v0.1.0). See the Directory of published versions
| Active as of 2022-03-10 |
JSON representation of the MolecularVariant logical model.
{
"resourceType" : "StructureDefinition",
"id" : "MolecularVariant",
"text" : {
"status" : "extensions",
"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Minimum and Maximum # of times the the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Additional information about the element\">Description & Constraints</a><span style=\"float: right\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"http://hl7.org/fhir/R4/help16.png\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant\" title=\"MolecularVariant resource\">MolecularVariant</a><a name=\"MolecularVariant\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/domainresource.html\">DomainResource</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Molecular Variant</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.molecularType\" title=\"The type of molecule (e.g., DNA, RNA, protein)\">molecularType</a><a name=\"MolecularVariant.molecularType\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Molecule type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation\" title=\"A representation for the Variant that is used as its primary definition.\">primaryRepresentation</a><a name=\"MolecularVariant.primaryRepresentation\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Primary Representation</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.identifier\" title=\"Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.\">identifier</a><a name=\"MolecularVariant.primaryRepresentation.identifier\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identifer</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck111.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.text\" title=\"Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.\">text</a><a name=\"MolecularVariant.primaryRepresentation.text\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Text</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.text.value\" title=\"Value for the textual representation\">value</a><a name=\"MolecularVariant.primaryRepresentation.text.value\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Value</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.text.system\" title=\"System that defines the nomenclature (including version, if applicable)\">system</a><a name=\"MolecularVariant.primaryRepresentation.text.system\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">System</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence\" title=\"Sequence based representation of a variant\">sequence</a><a name=\"MolecularVariant.primaryRepresentation.sequence\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.system\" title=\"The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)\">system</a><a name=\"MolecularVariant.primaryRepresentation.sequence.system\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">System</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_choice.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Choice of Types\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]\" title=\"Sequence used as a reference for defining the state expressed by the Variant\">referenceSequence[x]</a><a name=\"MolecularVariant.primaryRepresentation.sequence.referenceSequence_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Reference Sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span title=\"Datatype to support FHIR Genomics. This datatype supports representations like GRCH38.p13 Chromosome 1\">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-GenomeSequenceDesignation.html\">http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span title=\"Datatype to support FHIR Genomics. This datatype supports identifier/accession-style representations like GCA_000001405.28\">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-IdentifierSequenceDesignation.html\">http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_resource.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.interval\" title=\"Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).\">interval</a><a name=\"MolecularVariant.primaryRepresentation.sequence.interval\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-MolecularPreciseInterval.html\">http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Interval</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.referenceAllele\" title=\"The allele found in the Reference Sequence at the location specified by Interval.\">referenceAllele</a><a name=\"MolecularVariant.primaryRepresentation.sequence.referenceAllele\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-MolecularSequence.html\">Molecular Sequence</a>)</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Reference Allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.primaryRepresentation.sequence.alternateAllele\" title=\"The state of the sequence at the location specified by Interval, which defines this Variant.\">alternateAllele</a><a name=\"MolecularVariant.primaryRepresentation.sequence.alternateAllele\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-MolecularSequence.html\">Molecular Sequence</a>)</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Alternate Allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation\" title=\"Alternative representations of the variant that might be considered to be equivalent but which might contain ambiguity or imprecision. Lossless transformations between the Primary and Secondary Representation(s) are not guaranteed.\">secondaryRepresentation</a><a name=\"MolecularVariant.secondaryRepresentation\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Secondary Representation(s)<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.identifier\" title=\"Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.\">identifier</a><a name=\"MolecularVariant.secondaryRepresentation.identifier\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identifer</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck111.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.text\" title=\"Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.\">text</a><a name=\"MolecularVariant.secondaryRepresentation.text\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Text</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.text.value\" title=\"Value for the textual representation\">value</a><a name=\"MolecularVariant.secondaryRepresentation.text.value\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Value</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.text.system\" title=\"System that defines the nomenclature (including version, if applicable)\">system</a><a name=\"MolecularVariant.secondaryRepresentation.text.system\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">System</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence\" title=\"Sequence based representation of a variant\">sequence</a><a name=\"MolecularVariant.secondaryRepresentation.sequence\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.system\" title=\"The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)\">system</a><a name=\"MolecularVariant.secondaryRepresentation.sequence.system\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">System</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1011.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_choice.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Choice of Types\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]\" title=\"Sequence used as a reference for defining the state expressed by the Variant\">referenceSequence[x]</a><a name=\"MolecularVariant.secondaryRepresentation.sequence.referenceSequence_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Reference Sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10110.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span title=\"Datatype to support FHIR Genomics. This datatype supports representations like GRCH38.p13 Chromosome 1\">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-GenomeSequenceDesignation.html\">http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10100.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <span title=\"Datatype to support FHIR Genomics. This datatype supports identifier/accession-style representations like GCA_000001405.28\">referenceSequenceHttp://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-IdentifierSequenceDesignation.html\">http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_resource.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.interval\" title=\"Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).\">interval</a><a name=\"MolecularVariant.secondaryRepresentation.sequence.interval\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-MolecularPreciseInterval.html\">http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Interval</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.referenceAllele\" title=\"The allele found in the Reference Sequence at the location specified by Interval.\">referenceAllele</a><a name=\"MolecularVariant.secondaryRepresentation.sequence.referenceAllele\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-MolecularSequence.html\">Molecular Sequence</a>)</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Reference Allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.secondaryRepresentation.sequence.alternateAllele\" title=\"The state of the sequence at the location specified by Interval, which defines this Variant.\">alternateAllele</a><a name=\"MolecularVariant.secondaryRepresentation.sequence.alternateAllele\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-MolecularSequence.html\">Molecular Sequence</a>)</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Alternate Allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck01.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships\" title=\"Defines a relationship between the source Variant and a target Variant.\">relationships</a><a name=\"MolecularVariant.relationships\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Relationship to another Variant<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships.type\" title=\"Type of relationship (e.g., a genomic variant might have a relationship of 'predicted translation to' a variant expressed at the protein level)\">type</a><a name=\"MolecularVariant.relationships.type\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships.description\" title=\"Text description of the relationship\">description</a><a name=\"MolecularVariant.relationships.description\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Description</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_reference.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Reference to another Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-MolecularVariant-definitions.html#MolecularVariant.relationships.relatedVariant\" title=\"Target variant of the relationship\">relatedVariant</a><a name=\"MolecularVariant.relationships.relatedVariant\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/references.html\">Reference</a>(<a href=\"StructureDefinition-MolecularVariant.html\">Molecular Variant</a>)</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Related Variant</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"http://hl7.org/fhir/R4/help16.png\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
},
"url" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant",
"version" : "0.1.0",
"name" : "MolecularVariant",
"title" : "Molecular Variant",
"status" : "active",
"date" : "2022-03-10T10:18:50-06:00",
"publisher" : "Clinical Genomics",
"contact" : [
{
"name" : "Clinical Genomics",
"telecom" : [
{
"system" : "url",
"value" : "http://example.org/example-publisher"
}
]
}
],
"description" : "MolecularVariant resource",
"jurisdiction" : [
{
"coding" : [
{
"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
"code" : "001",
"display" : "World"
}
]
}
],
"fhirVersion" : "4.0.1",
"mapping" : [
{
"identity" : "rim",
"uri" : "http://hl7.org/v3",
"name" : "RIM Mapping"
}
],
"kind" : "logical",
"abstract" : false,
"type" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant",
"baseDefinition" : "http://hl7.org/fhir/StructureDefinition/DomainResource",
"derivation" : "specialization",
"snapshot" : {
"element" : [
{
"id" : "MolecularVariant",
"path" : "MolecularVariant",
"short" : "Molecular Variant",
"definition" : "MolecularVariant resource",
"min" : 0,
"max" : "*",
"base" : {
"path" : "DomainResource",
"min" : 0,
"max" : "*"
},
"constraint" : [
{
"key" : "dom-2",
"severity" : "error",
"human" : "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
"expression" : "contained.contained.empty()",
"xpath" : "not(parent::f:contained and f:contained)",
"source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
},
{
"key" : "dom-3",
"severity" : "error",
"human" : "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
"expression" : "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
"xpath" : "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
"source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
},
{
"key" : "dom-4",
"severity" : "error",
"human" : "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
"expression" : "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
"xpath" : "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
"source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
},
{
"key" : "dom-5",
"severity" : "error",
"human" : "If a resource is contained in another resource, it SHALL NOT have a security label",
"expression" : "contained.meta.security.empty()",
"xpath" : "not(exists(f:contained/*/f:meta/f:security))",
"source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
},
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
"valueBoolean" : true
},
{
"url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
"valueMarkdown" : "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
}
],
"key" : "dom-6",
"severity" : "warning",
"human" : "A resource should have narrative for robust management",
"expression" : "text.`div`.exists()",
"xpath" : "exists(f:text/h:div)",
"source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
}
],
"isModifier" : false,
"isSummary" : false,
"mapping" : [
{
"identity" : "rim",
"map" : "Entity. Role, or Act"
}
]
},
{
"id" : "MolecularVariant.id",
"path" : "MolecularVariant.id",
"short" : "Logical id of this artifact",
"definition" : "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
"comment" : "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "Resource.id",
"min" : 0,
"max" : "1"
},
"type" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl" : "string"
}
],
"code" : "http://hl7.org/fhirpath/System.String"
}
],
"isModifier" : false,
"isSummary" : true
},
{
"id" : "MolecularVariant.meta",
"path" : "MolecularVariant.meta",
"short" : "Metadata about the resource",
"definition" : "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "Resource.meta",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "Meta"
}
],
"constraint" : [
{
"key" : "ele-1",
"severity" : "error",
"human" : "All FHIR elements must have a @value or children",
"expression" : "hasValue() or (children().count() > id.count())",
"xpath" : "@value|f:*|h:div",
"source" : "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier" : false,
"isSummary" : true
},
{
"id" : "MolecularVariant.implicitRules",
"path" : "MolecularVariant.implicitRules",
"short" : "A set of rules under which this content was created",
"definition" : "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
"comment" : "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "Resource.implicitRules",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "uri"
}
],
"constraint" : [
{
"key" : "ele-1",
"severity" : "error",
"human" : "All FHIR elements must have a @value or children",
"expression" : "hasValue() or (children().count() > id.count())",
"xpath" : "@value|f:*|h:div",
"source" : "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier" : true,
"isModifierReason" : "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
"isSummary" : true
},
{
"id" : "MolecularVariant.language",
"path" : "MolecularVariant.language",
"short" : "Language of the resource content",
"definition" : "The base language in which the resource is written.",
"comment" : "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
"min" : 0,
"max" : "1",
"base" : {
"path" : "Resource.language",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "code"
}
],
"constraint" : [
{
"key" : "ele-1",
"severity" : "error",
"human" : "All FHIR elements must have a @value or children",
"expression" : "hasValue() or (children().count() > id.count())",
"xpath" : "@value|f:*|h:div",
"source" : "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier" : false,
"isSummary" : false,
"binding" : {
"extension" : [
{
"url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
"valueCanonical" : "http://hl7.org/fhir/ValueSet/all-languages"
},
{
"url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
"valueString" : "Language"
},
{
"url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
"valueBoolean" : true
}
],
"strength" : "preferred",
"description" : "A human language.",
"valueSet" : "http://hl7.org/fhir/ValueSet/languages"
}
},
{
"id" : "MolecularVariant.text",
"path" : "MolecularVariant.text",
"short" : "Text summary of the resource, for human interpretation",
"definition" : "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
"comment" : "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
"alias" : [
"narrative",
"html",
"xhtml",
"display"
],
"min" : 0,
"max" : "1",
"base" : {
"path" : "DomainResource.text",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "Narrative"
}
],
"constraint" : [
{
"key" : "ele-1",
"severity" : "error",
"human" : "All FHIR elements must have a @value or children",
"expression" : "hasValue() or (children().count() > id.count())",
"xpath" : "@value|f:*|h:div",
"source" : "http://hl7.org/fhir/StructureDefinition/Element"
}
],
"isModifier" : false,
"isSummary" : false,
"mapping" : [
{
"identity" : "rim",
"map" : "Act.text?"
}
]
},
{
"id" : "MolecularVariant.contained",
"path" : "MolecularVariant.contained",
"short" : "Contained, inline Resources",
"definition" : "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
"comment" : "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
"alias" : [
"inline resources",
"anonymous resources",
"contained resources"
],
"min" : 0,
"max" : "*",
"base" : {
"path" : "DomainResource.contained",
"min" : 0,
"max" : "*"
},
"type" : [
{
"code" : "Resource"
}
],
"isModifier" : false,
"isSummary" : false,
"mapping" : [
{
"identity" : "rim",
"map" : "N/A"
}
]
},
{
"id" : "MolecularVariant.extension",
"path" : "MolecularVariant.extension",
"slicing" : {
"discriminator" : [
{
"type" : "value",
"path" : "url"
}
],
"description" : "Extensions are always sliced by (at least) url",
"rules" : "open"
},
"short" : "Additional content defined by implementations",
"definition" : "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"alias" : [
"extensions",
"user content"
],
"min" : 0,
"max" : "*",
"base" : {
"path" : "DomainResource.extension",
"min" : 0,
"max" : "*"
},
"type" : [
{
"code" : "Extension"
}
],
"constraint" : [
{
"key" : "ele-1",
"severity" : "error",
"human" : "All FHIR elements must have a @value or children",
"expression" : "hasValue() or (children().count() > id.count())",
"xpath" : "@value|f:*|h:div",
"source" : "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key" : "ext-1",
"severity" : "error",
"human" : "Must have either extensions or value[x], not both",
"expression" : "extension.exists() != value.exists()",
"xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source" : "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier" : false,
"isSummary" : false,
"mapping" : [
{
"identity" : "rim",
"map" : "N/A"
}
]
},
{
"id" : "MolecularVariant.modifierExtension",
"path" : "MolecularVariant.modifierExtension",
"slicing" : {
"discriminator" : [
{
"type" : "value",
"path" : "url"
}
],
"description" : "Extensions are always sliced by (at least) url",
"rules" : "open"
},
"short" : "Extensions that cannot be ignored",
"definition" : "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
"alias" : [
"extensions",
"user content"
],
"min" : 0,
"max" : "*",
"base" : {
"path" : "DomainResource.modifierExtension",
"min" : 0,
"max" : "*"
},
"type" : [
{
"code" : "Extension"
}
],
"constraint" : [
{
"key" : "ele-1",
"severity" : "error",
"human" : "All FHIR elements must have a @value or children",
"expression" : "hasValue() or (children().count() > id.count())",
"xpath" : "@value|f:*|h:div",
"source" : "http://hl7.org/fhir/StructureDefinition/Element"
},
{
"key" : "ext-1",
"severity" : "error",
"human" : "Must have either extensions or value[x], not both",
"expression" : "extension.exists() != value.exists()",
"xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source" : "http://hl7.org/fhir/StructureDefinition/Extension"
}
],
"isModifier" : true,
"isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
"isSummary" : false,
"mapping" : [
{
"identity" : "rim",
"map" : "N/A"
}
]
},
{
"id" : "MolecularVariant.molecularType",
"path" : "MolecularVariant.molecularType",
"short" : "Molecule type",
"definition" : "The type of molecule (e.g., DNA, RNA, protein)",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.molecularType",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation",
"path" : "MolecularVariant.primaryRepresentation",
"short" : "Primary Representation",
"definition" : "A representation for the Variant that is used as its primary definition.",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.identifier",
"path" : "MolecularVariant.primaryRepresentation.identifier",
"short" : "Identifer",
"definition" : "Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.identifier",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.text",
"path" : "MolecularVariant.primaryRepresentation.text",
"short" : "Text",
"definition" : "Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.text",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.text.value",
"path" : "MolecularVariant.primaryRepresentation.text.value",
"short" : "Value",
"definition" : "Value for the textual representation",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.text.value",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "string"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.text.system",
"path" : "MolecularVariant.primaryRepresentation.text.system",
"short" : "System",
"definition" : "System that defines the nomenclature (including version, if applicable)",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.text.system",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence",
"path" : "MolecularVariant.primaryRepresentation.sequence",
"short" : "Sequence",
"definition" : "Sequence based representation of a variant",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.sequence",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.system",
"path" : "MolecularVariant.primaryRepresentation.sequence.system",
"short" : "System",
"definition" : "The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.sequence.system",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]",
"path" : "MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]",
"short" : "Reference Sequence",
"definition" : "Sequence used as a reference for defining the state expressed by the Variant",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"
},
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.interval",
"path" : "MolecularVariant.primaryRepresentation.sequence.interval",
"short" : "Interval",
"definition" : "Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.sequence.interval",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.referenceAllele",
"path" : "MolecularVariant.primaryRepresentation.sequence.referenceAllele",
"short" : "Reference Allele",
"definition" : "The allele found in the Reference Sequence at the location specified by Interval.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.sequence.referenceAllele",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.alternateAllele",
"path" : "MolecularVariant.primaryRepresentation.sequence.alternateAllele",
"short" : "Alternate Allele",
"definition" : "The state of the sequence at the location specified by Interval, which defines this Variant.",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.primaryRepresentation.sequence.alternateAllele",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation",
"path" : "MolecularVariant.secondaryRepresentation",
"short" : "Secondary Representation(s)",
"definition" : "Alternative representations of the variant that might be considered to be equivalent but which might contain ambiguity or imprecision. Lossless transformations between the Primary and Secondary Representation(s) are not guaranteed.",
"min" : 0,
"max" : "*",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation",
"min" : 0,
"max" : "*"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.identifier",
"path" : "MolecularVariant.secondaryRepresentation.identifier",
"short" : "Identifer",
"definition" : "Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.identifier",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.text",
"path" : "MolecularVariant.secondaryRepresentation.text",
"short" : "Text",
"definition" : "Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.text",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.text.value",
"path" : "MolecularVariant.secondaryRepresentation.text.value",
"short" : "Value",
"definition" : "Value for the textual representation",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.text.value",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "string"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.text.system",
"path" : "MolecularVariant.secondaryRepresentation.text.system",
"short" : "System",
"definition" : "System that defines the nomenclature (including version, if applicable)",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.text.system",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence",
"path" : "MolecularVariant.secondaryRepresentation.sequence",
"short" : "Sequence",
"definition" : "Sequence based representation of a variant",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.sequence",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.system",
"path" : "MolecularVariant.secondaryRepresentation.sequence.system",
"short" : "System",
"definition" : "The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.sequence.system",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]",
"path" : "MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]",
"short" : "Reference Sequence",
"definition" : "Sequence used as a reference for defining the state expressed by the Variant",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"
},
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.interval",
"path" : "MolecularVariant.secondaryRepresentation.sequence.interval",
"short" : "Interval",
"definition" : "Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.sequence.interval",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.referenceAllele",
"path" : "MolecularVariant.secondaryRepresentation.sequence.referenceAllele",
"short" : "Reference Allele",
"definition" : "The allele found in the Reference Sequence at the location specified by Interval.",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.sequence.referenceAllele",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.alternateAllele",
"path" : "MolecularVariant.secondaryRepresentation.sequence.alternateAllele",
"short" : "Alternate Allele",
"definition" : "The state of the sequence at the location specified by Interval, which defines this Variant.",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.secondaryRepresentation.sequence.alternateAllele",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.relationships",
"path" : "MolecularVariant.relationships",
"short" : "Relationship to another Variant",
"definition" : "Defines a relationship between the source Variant and a target Variant.",
"min" : 0,
"max" : "*",
"base" : {
"path" : "MolecularVariant.relationships",
"min" : 0,
"max" : "*"
},
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.relationships.type",
"path" : "MolecularVariant.relationships.type",
"short" : "Type",
"definition" : "Type of relationship (e.g., a genomic variant might have a relationship of 'predicted translation to' a variant expressed at the protein level)",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.relationships.type",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.relationships.description",
"path" : "MolecularVariant.relationships.description",
"short" : "Description",
"definition" : "Text description of the relationship",
"min" : 0,
"max" : "1",
"base" : {
"path" : "MolecularVariant.relationships.description",
"min" : 0,
"max" : "1"
},
"type" : [
{
"code" : "string"
}
]
},
{
"id" : "MolecularVariant.relationships.relatedVariant",
"path" : "MolecularVariant.relationships.relatedVariant",
"short" : "Related Variant",
"definition" : "Target variant of the relationship",
"min" : 1,
"max" : "1",
"base" : {
"path" : "MolecularVariant.relationships.relatedVariant",
"min" : 1,
"max" : "1"
},
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant"
]
}
]
}
]
},
"differential" : {
"element" : [
{
"id" : "MolecularVariant",
"path" : "MolecularVariant",
"short" : "Molecular Variant",
"definition" : "MolecularVariant resource"
},
{
"id" : "MolecularVariant.molecularType",
"path" : "MolecularVariant.molecularType",
"short" : "Molecule type",
"definition" : "The type of molecule (e.g., DNA, RNA, protein)",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation",
"path" : "MolecularVariant.primaryRepresentation",
"short" : "Primary Representation",
"definition" : "A representation for the Variant that is used as its primary definition.",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.identifier",
"path" : "MolecularVariant.primaryRepresentation.identifier",
"short" : "Identifer",
"definition" : "Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.text",
"path" : "MolecularVariant.primaryRepresentation.text",
"short" : "Text",
"definition" : "Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.text.value",
"path" : "MolecularVariant.primaryRepresentation.text.value",
"short" : "Value",
"definition" : "Value for the textual representation",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "string"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.text.system",
"path" : "MolecularVariant.primaryRepresentation.text.system",
"short" : "System",
"definition" : "System that defines the nomenclature (including version, if applicable)",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence",
"path" : "MolecularVariant.primaryRepresentation.sequence",
"short" : "Sequence",
"definition" : "Sequence based representation of a variant",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.system",
"path" : "MolecularVariant.primaryRepresentation.sequence.system",
"short" : "System",
"definition" : "The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]",
"path" : "MolecularVariant.primaryRepresentation.sequence.referenceSequence[x]",
"short" : "Reference Sequence",
"definition" : "Sequence used as a reference for defining the state expressed by the Variant",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"
},
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.interval",
"path" : "MolecularVariant.primaryRepresentation.sequence.interval",
"short" : "Interval",
"definition" : "Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.referenceAllele",
"path" : "MolecularVariant.primaryRepresentation.sequence.referenceAllele",
"short" : "Reference Allele",
"definition" : "The allele found in the Reference Sequence at the location specified by Interval.",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.primaryRepresentation.sequence.alternateAllele",
"path" : "MolecularVariant.primaryRepresentation.sequence.alternateAllele",
"short" : "Alternate Allele",
"definition" : "The state of the sequence at the location specified by Interval, which defines this Variant.",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation",
"path" : "MolecularVariant.secondaryRepresentation",
"short" : "Secondary Representation(s)",
"definition" : "Alternative representations of the variant that might be considered to be equivalent but which might contain ambiguity or imprecision. Lossless transformations between the Primary and Secondary Representation(s) are not guaranteed.",
"min" : 0,
"max" : "*",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.identifier",
"path" : "MolecularVariant.secondaryRepresentation.identifier",
"short" : "Identifer",
"definition" : "Identifer based representation of a variant. The source of the identifier is specified using the URI recorded in the system attribute.",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.text",
"path" : "MolecularVariant.secondaryRepresentation.text",
"short" : "Text",
"definition" : "Text based representation of a variant, including nomenclatures such as HGVS, ISCN, HLA, and pharmacogenetic star alleles.",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.text.value",
"path" : "MolecularVariant.secondaryRepresentation.text.value",
"short" : "Value",
"definition" : "Value for the textual representation",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "string"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.text.system",
"path" : "MolecularVariant.secondaryRepresentation.text.system",
"short" : "System",
"definition" : "System that defines the nomenclature (including version, if applicable)",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence",
"path" : "MolecularVariant.secondaryRepresentation.sequence",
"short" : "Sequence",
"definition" : "Sequence based representation of a variant",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.system",
"path" : "MolecularVariant.secondaryRepresentation.sequence.system",
"short" : "System",
"definition" : "The system that specifies how this information should be interpreted, since systems may include different business rules governing interpretation (e.g. VCF left shifts while HGVS right shifts)",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]",
"path" : "MolecularVariant.secondaryRepresentation.sequence.referenceSequence[x]",
"short" : "Reference Sequence",
"definition" : "Sequence used as a reference for defining the state expressed by the Variant",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/GenomeSequenceDesignation"
},
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/IdentifierSequenceDesignation"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.interval",
"path" : "MolecularVariant.secondaryRepresentation.sequence.interval",
"short" : "Interval",
"definition" : "Coordinates of the variant. Note the interpretation of these coordinates may be subject to system-specific business rules or conventions (e.g., 0-based or 1-based).",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularPreciseInterval"
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.referenceAllele",
"path" : "MolecularVariant.secondaryRepresentation.sequence.referenceAllele",
"short" : "Reference Allele",
"definition" : "The allele found in the Reference Sequence at the location specified by Interval.",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.secondaryRepresentation.sequence.alternateAllele",
"path" : "MolecularVariant.secondaryRepresentation.sequence.alternateAllele",
"short" : "Alternate Allele",
"definition" : "The state of the sequence at the location specified by Interval, which defines this Variant.",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularSequence"
]
}
]
},
{
"id" : "MolecularVariant.relationships",
"path" : "MolecularVariant.relationships",
"short" : "Relationship to another Variant",
"definition" : "Defines a relationship between the source Variant and a target Variant.",
"min" : 0,
"max" : "*",
"type" : [
{
"code" : "BackboneElement"
}
]
},
{
"id" : "MolecularVariant.relationships.type",
"path" : "MolecularVariant.relationships.type",
"short" : "Type",
"definition" : "Type of relationship (e.g., a genomic variant might have a relationship of 'predicted translation to' a variant expressed at the protein level)",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "CodeableConcept"
}
]
},
{
"id" : "MolecularVariant.relationships.description",
"path" : "MolecularVariant.relationships.description",
"short" : "Description",
"definition" : "Text description of the relationship",
"min" : 0,
"max" : "1",
"type" : [
{
"code" : "string"
}
]
},
{
"id" : "MolecularVariant.relationships.relatedVariant",
"path" : "MolecularVariant.relationships.relatedVariant",
"short" : "Related Variant",
"definition" : "Target variant of the relationship",
"min" : 1,
"max" : "1",
"type" : [
{
"code" : "Reference",
"targetProfile" : [
"http://hl7.org/fhir/uv/cg-model/StructureDefinition/MolecularVariant"
]
}
]
}
]
}
}